Annotation Overview for fig|195099.3.peg.1371 in Campylobacter jejuni RM1221:
S-ribosylhomocysteine lyase (EC 4.4.1.21) / Autoinducer-2 production protein LuxS

current assignment	This feature plays multiple roles which are implemented by distinct domains within the feature. The roles are: S-ribosylhomocysteine lyase (EC 4.4.1.21) EC Number 4.4.1.21 Autoinducer-2 production protein LuxS S-ribosylhomocysteine lyase (EC 4.4.1.21) / Autoinducer-2 production protein LuxS
taxonomy id	195099	contig	195099.3:NC_003912 (1,777,832bp)
internal links	genome browser | feature evidence | sequence	ACH Annotation Clearinghouse (ACH) The Annotation Clearinghouse offers a mapping of genes which are identical in sequence except for the start region (due to differences in start calling). [?]	show essentially identical genes
annotation history		run tool	Psi-BlastTMpredTMHMMGram negative PSORTGram negative SignalPGram positive PSORTGram positive SignalPLipoPInterProScanRadarPPSearchGram negative CELLOGram positive CELLOProDomPDB
FigFam	FIG000845
data base cross references (dbxref)	NCBI: 73621183 CMR: CJE_1332 NCBI: 57238070 UniProt: LUXS_CAMJR RefSeq: YP_179319.1 NCBI: 57166874 UniProt: Q5HTR6

Annotation History (history of similar genes)

Date	Annotator	Annotation
4/24/2005	For	Set FIG function to Ribosylhomocysteinase (EC 3.2.1.148) / Autoinducer-2 production protein LuxS
3/21/2008	OlgaZ	Set FIG function to S-ribosylhomocysteine lyase (EC 4.4.1.21) / Autoinducer-2 production protein LuxS

The encoded protein plays multiple roles which are implemented by distinct domains within the feature. The roles are "S-ribosylhomocysteine lyase (EC 4.4.1.21)" and "Autoinducer-2 production protein LuxS". The protein occurs in 1 subsystem: "Methionine Biosynthesis". In "Methionine Biosynthesis", it appears to play a functional role that we have not associated with any other gene. The function of genes having the same functional roles have been described in Vibrio harveyi (9990077), Campylobacter jejuni (11988522), Listeria monocytogenes (16597969, 16885324) and Bacillus subtilis (12705835). These are homologous proteins which implement the same function.

The chromosomal region of the focus gene (top) is compared with four similar organisms. The graphic is centered on the focus gene, which is red and numbered 1. Sets of genes with similar sequence are grouped with the same number and color. Genes whose relative position is conserved in at least four other species are functionally coupled and share gray background boxes. The size of the region and the number of genomes may be reset. Click on any arrow in the display to refocus the comparison on that gene. The focus gene always points to the right, even if it is located on the minus strand.